Quick Answer: Yes, Tymlos must be refrigerated before first use (36°F-46°F). After opening, it can be kept at room temperature (68°F-77°F) for up to 30 days. Never freeze or expose it to heat. Proper storage ensures the medication stays safe and effective.
If you've recently been prescribed Tymlos as part of your osteoporosis treatment, you've probably been told to keep it in the fridge. Indeed, your injectable medicine is highly sensitive to temperature conditions and can quickly spoil if not stored correctly.
Therefore, meticulously following storage instructions is essential. The success of your treatment and, eventually, your health depend on it. So, let's zoom in on Tymlos storage recommendations. How exactly should you store your pens at home? Why do they need to be refrigerated? How long can they stay at room temperature? How to make sure your pens are cool when traveling?
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What is Tymlos?
Tymlos is an FDA-approved prescription medicine used to treat postmenopausal women with osteoporosis who are at high risk for bone fractures.
Here's what you should know:
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Osteoporosis is a chronic condition that weakens bones, making them more prone to fractures due to reduced bone density and mass.
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Tymlos contains abaloparatide, a synthetic form of parathyroid hormone that helps stimulate bone growth and increase bone strength.
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It comes as a prefilled injector pen with 30 doses (80 micrograms each) - enough for one month of daily use.
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Tymlos is injected subcutaneously (under the skin), typically in the stomach or abdominal area.
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ike all prescription medications, Tymlos may cause serious side effects. Always consult your doctor before use.
Related article: How to store Forteo for maximum efficiency?
Differences between Tymlos and Forteo
Tymlos (abaloparatide) and Forteo (teriparatide) are two injectable medicines used to treat osteoporosis. Both are synthetic forms of parathyroid hormone protein. Forteo has been on the market for longer and has a broader range of FDA-approved uses.
It can be prescribed to men with osteoporosis, whereas Tymlos has only been approved for women. Only your healthcare provider can help you decide what osteoporosis medication is best for you.
Does Tymlos need to be Refrigerated?
Patients are responsible for self-administering their daily dose of Tymlos. While the injection device is fairly simple to use and comes with straightforward instructions, one must be very careful to store their Tymlos pens at home properly.
Indeed, abaloparatide is a temperature-sensitive drug that requires refrigeration before first useand protection from heat once opened
Tymlos storage instructions
Proper storage is essential to keep Tymlos effective and safe to use. Here's what the manufacturer, Radius Health, recommends:
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Before first use, Tymlos pens must be stored in the refrigerator at 36°F to 46°F (2°C to 8°C).
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After first use, they can be kept at room temperature - between 68°F and 77°F (20°C to 25°C) - for up to 30 days.
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Do not expose pens to heat above 77°F (25°C) or freeze them.
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If a pen freezes, it's no longer safe - even if it thaws later.
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Avoid exposure to light, as it can degrade the active ingredient. Always store pens with the opaque cap on.
Regardless of how much medicine is left, discard each pen after 30 days from the first use.
Incorrect storage - even briefly - can degrade the medication, reducing or eliminating its effectiveness and potentially putting your health at risk.
How long can Tymlos be out of the fridge?
As mentioned above, Tymlos can be unrefrigerated for a maximum of 30 days. However, that does not free you from being cautious about its storage conditions, as your pens should never be exposed to temperatures above 77°F (25°C).
People who live in or travel to places where the ambient temperature may reach that threshold must use a cooling solution for their injector pens.
Related article: At what temperatures should you keep refrigerated medications?
How to travel with Tymlos pens?
One key advantage of Tymlos over similar medications is its 30-day room temperature stability, compared to Forteo, which must be refrigerated after just 36 hours.
Still, if you're traveling:
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To warm climates where temperatures might exceed 77°F (25°C),
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Or for longer than a month, bringing unopened Tymlos pens,you'll need a reliable cooling solution to protect your medication.
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Related article: How to travel with refrigerated medications?
📌 Key Takeaways:
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❄️ Tymlos must be refrigerated (36°F-46°F) before first use to preserve its effectiveness.
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🌡️ After opening, pens can be stored at room temperature (68°F-77°F) for up to 30 days.
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🚫 Avoid freezing or exposing Tymlos to heat, as it can degrade the medicine.
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🧳 Use travel coolers to keep Tymlos safe on the go, especially in warm climates.
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🕒 Discard any pen 30 days after first use, even if it's not empty.
💬 We'd Love to Hear From You!
Whether you're new to Tymlos or a seasoned user, your thoughts matter. Got tips, questions, or experiences about storing or traveling with Tymlos? Share them below or reach out - we're here to support your journey to better bone health!
📆 Article Update History:
✅ Updated: April 24, 2025
Originally Published: February 08, 2023
Comments
4AllFamily Customer Service said:
Hello Lois,
Once a Tymlos pen is opened, it can only be used for up to 30 days, regardless of whether it has been kept in the fridge or at room temperature during that period. If the pen was used and then put back in the refrigerator for a few weeks, it is important to check how many days in total it has been since it was first opened. If it has been more than 30 days, the medication should not be used and should be disposed of to ensure safety and effectiveness. Always be sure to track the opening date and adhere strictly to the 30-day usage window for best results.
Warm regards,
4AllFamily
Lois Fore said:
If a tymlos pen was refrigerated, then used and put back in the refrigerator for a few weeks can the medicine still be used?
4AlLFamily Customer Care Team said:
Hello Rose,
Thanks for reaching out with your questions. Regarding your Tymlos injections, as long as they have been stored properly in the refrigerator and the expiration date labeled on the pens has not passed, it should be safe to use. But make sure you do not use the medication after its expiration date.
As for financial assistance for Tymlos, we do not have specific contact details. It’s a good idea to contact the manufacturer directly for any savings programs they may offer. Your pharmacist may also have information about potential coupons or discounts, and it’s worth discussing with your insurer to see if they provide any support.
Best wishes,
4AllFamily
Rose Broderick said:
I have tymlos medication from February 2023. I have keep it refrigerated and have not used. Can I use it and 2 other pens not used since then. I also need financial assistance to get more Tymlos. What is the telephone #? I believe it’s Radius Assistance.