If you’ve recently been prescribed Tymlos as part of your osteoporosis treatment, you've probably been told to keep it in the fridge. Indeed, your injectable medicine is highly sensitive to temperature conditions and can quickly spoil if not stored correctly.
Therefore, meticulously following storage instructions is essential. The success of your treatment and, eventually, your health depend on it.
So, let's zoom in on Tymlos storage recommendations. How exactly should you store your pens at home? Why do they need to be refrigerated? How long can they stay at room temperature? How to make sure your pens are cool when traveling?

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What is Tymlos?

Tymlos is the brand name of an FDA-approved prescription medicine used to treat menopausal women with osteoporosis at high risk for bone fractures. Osteoporosis is a chronic bone disease that causes the bones to break more easily than usual due to decreased bone mineral density and mass.
The active drug in Tymlos is abaloparatide. It's a synthetic form of a naturally occurring hormone called parathyroid hormone. The anabolic medicine works by boosting your body’s natural bone-building process to increase bone density and strength and help prevent fractures.
Tymlos is a liquid injectable medication that comes in prefilled injector pens containing about a month's worth of medicine (30 doses of 80 micrograms). It’s usually administered daily through subcutaneous injections (under the skin in the stomach or abdomen).
Tymlos may cause serious side effects. Never take this medication without your doctor’s advice.
Related article: How to store Forteo for maximum efficiency?

Differences between Tymlos and Forteo 

Tymlos (abaloparatide) and Forteo (teriparatide) are two injectable medicines used to treat osteoporosis. Both are synthetic forms of parathyroid hormone protein. Forteo has been on the market for longer and has a broader range of FDA-approved uses. It can be prescribed to men with osteoporosis, whereas Tymlos has only been approved for women.
Only your healthcare provider can help you decide what osteoporosis medication is best for you.
Related article: How to keep your Forteo pens cool while traveling?

Does Tymlos need to be Refrigerated?

Patients are responsible for self-administering their daily dose of Tymlos. While the injection device is fairly simple to use and comes with straightforward instructions, one must be very careful to store their Tymlos pens at home properly.
Indeed, abaloparatide is a temperature-sensitive drug that requires refrigeration before first useand protection from heat once opened.

Tymlos storage instructions

According to Radius Health, the manufacturer of Tymlos, Tymlos pens must be stored in the refrigerator between 36°F and 46°F (2°C and 8°C) before first use.
After first use, they do not need to be refrigerated and can be “stored for up to 30 days at room temperature, between 68°F and 77°F (20°C and 25°C).”
In no case should Tymlos pens be exposed to heat and temperatures above 77°F (25°C). Besides, the pens must be thrown away after 30 days, even if there’s still medicine inside.
You must also ensure your injection pens do not freeze, as freezing temperatures can destroy the medicine inside. Never use Tymlos that has frozen, even if it has thawed afterward.
Exposure to light can also degrade abaloparatide. That’s why the pen’s cap is opaque. Always store your pens with the cap on.
Bear in mind that storing your Tymlos pens correctly is crucial to your health. When unrefrigerated for more than 30 days or exposed to high temperatures, even briefly, Tymlos starts degrading, leading to a partial or total loss of efficiency. Eventually, you would receive a lower or no dose of your treatment, which can seriously affect your health.

How long can Tymlos be out of the fridge?

As mentioned above, Tymlos can be unrefrigerated for a maximum of 30 days. However, that does not free you from being cautious about its storage conditions, as your pens should never be exposed to temperatures above 77°F (25°C).
People who live in or travel to places where the ambient temperature may reach that threshold must use a cooling solution for their injector pens.

How to travel with Tymlos pens?

Since Tymlos can last up to 30 days without refrigeration, it’s less of a hassle than Forteo, which can only be left unrefrigerated for 36 hours.
Yet, traveling with Tymlos pens requires some precautions to ensure your in-use pen stays cool and your stock of unopened ones is refrigerated (if you’re traveling for more than a month). And that's where 4AllFamily comes in.
Our company designs medical-grade travel coolers for refrigerated drugs like Tymlos, Forteo, insulin, Ozempic, growth hormones, Mounjaro, and many others. Thousands of people whose health depends on fragile medications have trusted our products for years.
Whether you’re a business traveler, beach lover, adventurous backpacker, or museum addict, there's a convenient and reliable cooler to keep your Tymlos pens cool or refrigerated, safe, and effective!

4AllFamily portable cooling cases for cold medications like Tymlos, Forteo

Browse through our catalog here, and feel free to reach out if you have any doubts or need any advice. We're here to help!
Related article: How to travel with refrigerated medications?

February 08, 2023


4AlLFamily Customer Care Team said:

Hello Rose,
Thanks for reaching out with your questions. Regarding your Tymlos injections, as long as they have been stored properly in the refrigerator and the expiration date labeled on the pens has not passed, it should be safe to use. But make sure you do not use the medication after its expiration date.

As for financial assistance for Tymlos, we do not have specific contact details. It’s a good idea to contact the manufacturer directly for any savings programs they may offer. Your pharmacist may also have information about potential coupons or discounts, and it’s worth discussing with your insurer to see if they provide any support.
Best wishes,

Rose Broderick said:

I have tymlos medication from February 2023. I have keep it refrigerated and have not used. Can I use it and 2 other pens not used since then. I also need financial assistance to get more Tymlos. What is the telephone #? I believe it’s Radius Assistance.

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The information presented in this article and its comment section is for informational purposes only and is not intended as a replacement for professional medical advice. Always consult with a qualified healthcare provider for any medical concerns or questions you may have.