Whether you’re commuting, traveling, or just stepping out for the day, carrying your eye drops at a controlled temperature is important for their effectiveness.

So, let’s dive into how you can keep your eye drops cool, no matter where you are, and why an eye drop carrying case is an essential item to have, especially during summertime!

4AllFamily Eye Drop Coolers

Related article: Can You Bring Eye Drops on a Plane? Packing Tips for Air Travel!

Why You Need an Eye Drop Carrying Case Cooler

Many eye drops, especially those prescribed for eye conditions like glaucoma or severe dry eye, contain sensitive ingredients that must be kept cool within specific temperature ranges to remain effective.

Exposing these ophthalmic solutions to temperatures above 25°C (77°F) can often alter their chemical structure, potentially reducing their effectiveness or even rendering them unsafe for use.

Besides, some eye drops, like Latanoprost (Xalatan, Xelpros) and others must be refrigerated, especially before opening.

That's why carrying your eye drops in a cooler is essential, particularly if you're living in or traveling to hot weather places.

Related article: Should You Keep Your Eye Drops in the Fridge?

List of eye drops that need refrigeration or temperature control

With hundreds of different types and brands of eye drops available in the U.S., it's challenging to compile a comprehensive list of those that require refrigeration or controlled temperature storage. So, always consult your eye drops’ specific storage instructions before traveling or stepping out for the day.

As a rule, however, pretty much all eye drops must be stored and transported at a controlled temperature below 25°C (77°F). Exposure to heat above this threshold could significantly alter their chemical structure and reduce the effectiveness of your treatment.

However, some eye drops have even stricter requirements and need to be refrigerated between 2°C and 8°C (35°F to 46°F), typically before they are first opened. These include, but are not limited to:

  • Xalatan Latanoprost glaucoma eye drops must be refrigerated before opening. They can be kept at room temperature below 25°C (77°F) for up to 6 weeks.
  • Xelpros Latanoprost glaucoma eye drops must also be refrigerated before use. The bottle can be kept at room temperature up to 40°C (104°F) for a maximum of 8 days.
  • Xalacom eye drop bottle must be refrigerated before first use. It can then be stored at room temperature below 25°C (77°F) for up to 4 weeks.
  • Rocklatan has the same storage instructions but is good for up to 6 weeks after opening.
  • Tacrolimus eye drops for Keratoconjunctivitis Sicca must be refrigerated too. Once opened, some formulations allow for room-temperature storage, but it depends on the preservatives use.
  • Serum eye drops must generally be stored in a freezer and can stay refrigerated for a limited time. They should never be kept out at room temperature.
  • Other eye drops that require refrigerated storage include Cyclosporine, Fluorescein, IGF-1, Ceftazidime, Ganciclovir, Bevacizumab, Fortified tobramycin, Gentamicin, Vitamin A eye drops, and others.

Related article: Detailed Storage Guide to Keep Latanoprost Eye Drops Safe!

Choosing the Right Eye Drop Cooler

Choosing the right eye drop carrying case involves more than just popping your drops in an insulated lunch bag with a few ice cubes.

Firstly, direct contact with ice isn’t recommended because it risks freezing your medication, which could render it ineffective. Secondly, these DIY cooler bags aren’t reliable enough for transporting eye drops due to their inability to maintain a stable internal temperature, which can lead to significant fluctuations and compromise the effectiveness of your eye medication.

If you’re a frequent traveler or often need to carry your eye drops with you, investing in a reliable, medical-grade eye drop cooler is a wise decision. These specialized carrying cases are designed to protect your medication from heat and ensure they remain safe and effective regardless of external temperatures

But before purchasing the first eye drop cooler you come across on Amazon, consider the following factors:

  • Temperature requirements: Will you need to carry refrigerated eye drops between 2°C and 8°C (35°F to 46°F), or simply keep them below 25°C (77°F)?
  • Duration of temperature control: How long will you need your eye drops to stay cool? Whether it’s just for a few hours or several days, ensure your cooler can maintain the required temperature for the entire duration of your outing. 
  • Cooler capacity: How many bottles of eye drops do you need to carry throughout your trip? Select an eye drop carrying case cooler that is compact and portable, yet spacious enough to fit all your eye drop bottles comfortably.
  • Cooling mechanism: Do you prefer a cooler that uses cold packs, or would a USB-powered travel mini fridge be more suitable? Determine whether you’ll have access to a freezer or USB power during your travels. Alternatively, consider the convenience of evaporative cooling wallets for eye drops which require only water to keep your eye drops cool for several days!

4AllFamily Eye Drop Coolers & Carrying Cases

4AllFamily specializes in providing travel cooling solutions for medications and eye drops that require refrigerated or temperature-controlled storage during transport. Here are our customers’ favorite coolers for carrying eye drops:

The Chillers Eye Drop Cooling Wallets

Our top choice for keeping eye drops cool at room temperature below 25°C (77°F) is the Chillers Cooling Wallets.

Chillers Eye Drop Cooling Wallets, 4AllFamily
These compact yet highly effective medical-grade cooling bags utilize advanced evaporative cooling technology to maintain a consistent cool environment, perfect for insulin, EpiPens, and of course, eye drops.

Lightweight and portable, the Chillers slip effortlessly into your purse or backpack. They operate with simple water activation system, requiring no electricity or freezer to keep your eye drops cool.  All you need is water, making them the ideal eye drop coolers for any travel situation, even in the most remote places where power might not be readily available.

To activate, simply soak the inner wallet in water for 20-30 minutes and get 45+ hours of cooling for your eye drops. The best part? You can reactivate the wallet as needed, providing reliable and continuous cooling for your eye drops throughout your travels, lasting days, weeks, or even months!

The Companion Eye Drop Cooler Bag

For those needing to carry numerous bottles of eye drops or large containers at room temperature below 25°C (77°F), the Companion Insulated Cooler Bag is your best bet.

Companion Eye Drop Cooler Bag 4AllFamily

This cooler bag works with high-efficiency cold packs that need to be frozen before use. It offers spacious storage and can keep your eye drops cool at room-temperature for up to 10 hours at 104°F (40°C), 12 hours at 95°F (35°C), or 14 hours at 86°F (30°C). And, like all our eye drop coolers, it’s TSA-approved for air travel!

Refrigerated Eye Drop Travel Cases

If you need to carry refrigerated eye drops – such as serum eye drops or unopened bottles of Latanoprost - check out our powerful refrigerated travel cases that provide optimal fridge-like temperatures between 2°C and 8°C (35°F to 46°F) throughout your journey.

Our selection of eye drop coolers includes versatile models to suit every need:

Unsure which cooler is the right fit for your eye drops? Don’t hesitate to contact us. We’re eager to guide you through our extensive range of eye drop cooling cases and help you find the perfect match for your needs!

4AllFamily Eye Drop Cooling Cases


More Tips to Keep Eye Drops Cool When Traveling

Even with the best eye drop cooler, keeping your eye drops cool when traveling requires some extra precautions. So, below are a few additional tips and best practices for traveling with temperature-sensitive eye drops:

  • Always store in the shade: Always store your eye drop carrying case in a shaded area, away from direct sunlight which can quickly heat up your medications and reduce the performance of your eye drop cooler.
  • Avoid direct sunlight. Always keep your eye drops away from direct sunlight. Exposure to light, even in the cold, can damage your eye medication.
  • Minimize exposure. Only remove your eye drops from their cooler when necessary. If you are out for the day, consider leaving your eye drops in your hotel room or at home if you won’t need them until you return. This helps minimize exposure to varying temperatures and ensures that the eye drops are kept in a controlled environment as much as possible.
  • Have a back-up plan. Always carry extra supplies of your eye drops to prepare for any unforeseen events such as loss, theft, or damage to a bottle. Keep your prescription handy in case you need to purchase additional eye drops at your destination.

By following these guidelines, you can ensure that your eye drops stay cool and safe, wherever you’re traveling to. So go ahead, pack your bags, grab your eye drop cooler, and step out with confidence knowing your eye care is in good hands!

Related article: Is Flying with Glaucoma Safe?

We’d Love to Hear From You!

Please share your experiences, questions, or tips for traveling with eye drops in the comments below. What are your favorite eye drop coolers? Your insights could help others!

April 28, 2022


4AllFamily Customer Care Team said:

Hi B.Parsons,
Thank you for your comment! Two of our coolers are specifically designed to keep meds at room temperature below 77 (not refrigerated), please check at the Rambler: https://4allfamily.com/products/4allfamily-10h-1-pen-insulin-pen-travel-cooler-pocket-size-daily-use-lightweight
and the Companion: https://4allfamily.com/products/4allfamily-soft-case-open-medicine-travel-cooler-diabetic-supplies-insulin-travel-case-travel-medicine-kit-tsa-insulin-case-portable-medical-storage-diabetes-travel-case
I think these may be best for your needs.
All the best,
4AllFamily Customer Care Team

B. Parsons said:

This site was very helpful. May be going camping in mid July and our cabin has no AC. Just looking for something to control temp for eye drops between 68-77 . I know this probably isn’t something you can help with based on your focus on needs with lower temp requirements but just checking in case we run into 90 degree weather. Planning ahead! Thank you!

Kay B said:

Perfect. Very informative. My thanks to you all.

Leave a comment

Please note: comments must be approved before they are published.

The information presented in this article and its comment section is for informational purposes only and is not intended as a replacement for professional medical advice. Always consult with a qualified healthcare provider for any medical concerns or questions you may have.