Quick Answer: To travel safely with Trimix injections, keep them refrigerated between 36°F-46°F using a medical-grade cooler. Never leave them at room temperature for more than 24 hours, and always pack them in your carry-on with a copy of your prescription for TSA security.
If you are traveling with Trimix, you must take steps to keep it cool and ensure it remains effective. Indeed, like most penile injections, Trimix can only stay unrefrigerated for a few hours. So, let's go through our series of essential tips for ensuring your drug's effectiveness while enjoying your travels!
Related article: A Step-by-Step Guide to Injecting Trimix Correctly!
Trimix Storage Instructions: Reminder!
Trimix is a medication commonly used to treat erectile dysfunction. It contains a combination of three active drugs (alprostadil, papaverine, and phentolamine) administered via penile injections.
While Trimix is an effective treatment, these drugs are quite unstable and require proper storage to maintain their potency and efficiency. As a rule of thumb, Trimix must be stored and transported as follows:
- Open in-use Trimix vials should be stored in the refrigerator at 36°F - 46°F (2°C - 8°C) for about one month.
- They can be left at room temperature for short periods of time only (up to 24 hours at the most)
- Stocks of unopened Trimix vials should be stored in the freezer at 0°F - 31°F (-18°C - 0°) and can last for 6 months and up to one year.
Different compounding pharmacies manufacture Trimix with varying dosage. Your Trimix vials may have a different shelf life and temperature recommendations depending on its specific composition. Always refer to the storage instructions delivered with your medication.
How to Keep Trimix Cold While Traveling?
These strict storage conditions make traveling with Trimix challenging, as it can only stay at room temperature for a few hours. Travelers then need to find a way to transport their injections refrigerated (or frozen if traveling for over a month). A medical-grade travel cooler is an essential item for anyone traveling with Trimix.
Use a Trimix travel case
4AllFamily designs travel coolers for people who rely on refrigerated drugs like Trimix. We offer high-performing portable refrigerators that keep your penile injections refrigerated for up to several days (when running on battery power) or unlimited time (when plugged into a power source).
Depending on your lifestyle and the kind of travel you're planning, you can choose from a wide range of products to accommodate your needs.
Related article: Trimix Storage Guide: How to Properly Freeze, Refrigerate, and Preserve Potency for Safe and Effective Treatment
The Chillers are cooling pouches that work without ice or electricity. All you need to make your Chiller work is water, so they're perfect for any travel situations, even in the most remote places.
These medical cooling bags keep your syringes cool within the safe temperature range of 64.4°F-79°F (18°C-26°C) for at least 45 hours, even in scorching summer temperatures as high as 100°F (37.8°C)!
Available in different sizes, you can carry from 1 to 5 prefilled syringes or numerous vials of medicine.
If you're looking for something a bit more basic, meet our Nomad Cooling bottle! It can hold up to 4 x 10mL vials of Trimix and keep them cold like in a fridge (36°F - 46°F (2°C - 8°C)) for 30 hours when it's 95°F / 35°C outside!
With its large capacity, the Voyager is a good option if you're traveling with many vials of Trimix. It works with 3 different cooling methods to accommodate any travel situation, from the most luxurious to the most adventurous.
- USB power + Freeze packs: it keeps fridge temperature for up to 50 hours when it's 104°F (40°C).
- Freeze packs only (no electricity): your Trimix vials will be safe and refrigerated for 28 hours!
- USB power only (no freeze packs): the travel fridge maintains constant fridge temperature when the outside temperature is no higher than 95°F / 35°C!
The Rambler compact syringe travel case cooler weighs only 0.7 lbs and fits into your purse! It's ideal for carrying one prefilled syringe during hot summer days, daily activities, school trips, etc.
It works with a pre-freezed biogel cold pack, and keeps insulin or any medicine cool and protected from the heat below 79°F (26°C) for up to 16 hours when the ambient temperature is 86°F (30°C) or 12 hours if it's 104°F (40°C).
The Explorer features three innovative cooling methods in one single travel case! You can used it with USB power like a car's cigarette lighter, USB solar panel, portable power bank, or AC household power. For non-electric cooling, switch the lid and use the biogel cold packs to keep your syringes cool. Or combine both the USB lid and biogel packs for extended cooling!
It can keep prefilled syringes and vials of medicine refrigerated between 36-46°F / 2-8°C for up to 52 hours and cool below 79°F / 26°C for 72 hours.
The Explorer offers ample storage space to carry numerous syringes.
Our newest travel coolers - RxCooler Max and Mini - are built for safe, reliable Trimix storage on the go. Both use USB power and biogel packs for flexible cooling and keep meds between 36-46°F (2-8°C).
The Mini is compact and perfect for short trips, while the Max offers extra capacity for extended travel. TSA-approved and travel-ready, they make managing your medication effortless wherever you go.
All our travel coolers are TSA-approved for airplane travel, so you can legally board the plane with your Trimix vials refrigerated in your carry-on bags. We're here to help. Should you have any doubts or inquiries, please leave a comment below or contact us.
Related article: How to Travel with Refrigerated Medications?
Freeze Trimix before traveling
To extend the shelf life of your Trimix vials while traveling, you can freeze them 24 hours before departure. That would ensure your drug remains colder for longer. If it's already frozen, take it out of the freezer at the last minute and put it in your travel cooler immediately.
Warning: Do not refreeze Trimix! Thawing and refreezing Trimix repeatedly is not recommended.
Keep your injections out of direct sunlight
Direct sunlight can cause your medication to overheat and lose its effectiveness. Therefore, always keep Trimix in a shaded area. Also, avoid leaving your medicines in the car, especially in hot climates, and only take them outside your cooler when needed.
Use a thermometer to monitor the temperature
4AllFamily's RxCoolers Max, RxCoolers Mini and Voyager travel fridges are equipped with an integrated thermostat and a temperature display. But if you decide to use a DIY travel cooler, make sure to monitor the temperature inside regularly and adjust ice packs as necessary. Cooler bags made with insulated lunch bags and ice aren't reliable enough to travel with Trimix injections as the temperature inside is fluctuating a lot.
More Tips for Traveling with Trimix Injections
If you're flying with Trimix, there are a few important things to keep in mind to ensure a smooth, hassle-free trip:
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Always pack your Trimix in your carry-on bag - never in checked luggage, where temperature and handling are less controlled.
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Keep the medication in its original packaging, clearly labeled.
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Bring a copy of your prescription to present if requested during screening.
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You're allowed to carry injectable medications (even in amounts over 3.4 oz), as long as you declare them at the TSA checkpoint.
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Syringes needed for your injections are also permitted in carry-on luggage.
Following these steps will help ensure your Trimix remains safe, effective, and compliant with the Transportation and Security Administration (TSA) regulations while you travel.
Related article: How to Travel with Syringes & Injectable Drugs?
📌 Key Takeaways:
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❄️ Trimix must stay cold: Keep injections between 36°F-46°F and never leave unrefrigerated for over 24 hours.
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🧳 Use a medical travel cooler: Devices like the Pioneer, Nomad, or Voyager help maintain proper Trimix storage while traveling.
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✈️ Follow TSA guidelines: Carry Trimix in your hand luggage with original packaging and prescription; syringes are allowed.
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☀️ Avoid heat and sunlight: Direct exposure can degrade medication-store in shaded, cool places only.
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🧊 Freeze vials before departure: For longer trips, frozen Trimix lasts longer but do not refreeze once thawed.
💬 We'd Love to Hear From You!
Have questions about traveling with Trimix? Tried one of our recommended coolers? Share your experience, tips, or concerns in the comments below! We're here to help and would love to hear your thoughts. Safe travels!
📆 Article Update History:
✅ Updated: April 25, 2025
Originally Published: May 03, 2023
