Quick Answer: You can safely travel with Dupixent by keeping it refrigerated between 36°F and 46°F using a TSA-approved medical cooler. Always pack it in your carry-on and bring a prescription or doctor's note, especially for international trips. Proper storage and documentation ensure hassle-free travel with your medication.

Dupixent is the brand name of dupilumab, an FDA-approved drug used to treat symptoms of various chronic health conditions, including eczema, asthma, eosinophilic esophagitis, and others.

If you've been prescribed Dupixent, you must know your medicine requires specific storage conditions, constant refrigeration, and protection from heat and light.

What happens if your next injection occurs while traveling or away from home? How to travel or fly with refrigerated medications like Dupixent? How to make sure it stays cool even when you don't have access to a fridge? What documents should you bring with you?

Our team of experts answers all your questions here.

Related article: How long can Dupixent stay out of the fridge without going bad?

4AllFamily USA portable fridges and coolers for refrigerated drugs like Dupixent

Prefer Video Over Text?For those who'd rather watch than read, we've got you covered! Below is a video summary of this article for a quick and engaging overview. Enjoy!

How to keep Dupixent refrigerated while traveling?

Dupixent (dupilumab) is a biological medication made from living organisms, which makes it especially sensitive to temperature and light. To stay safe and effective, it must be stored properly-even when you're on the go.

Here's what you need to know to protect your Dupixent while traveling:

  • Keep it refrigerated: According to Regeneron Pharmaceuticals and Sanofi Genzyme, the manufacturers of Dupixent, unopened Dupixent must be stored in the fridge between 36°F and 46°F (2°C and 8°C) until its expiration or use.

  • 14-day rule: Once removed from the fridge, you have 14 days to use it. During that time, it must be kept at room temperature (below 77°F / 25°C) and protected from direct sunlight.

  • Avoid heat exposure: If Dupixent is exposed to temperatures above 77°F (25°C) or direct sunlight-even briefly-it may no longer be safe or effective.

  • No re-refrigeration: Once the pen or syringe has been out of the fridge, do not return it to the refrigerator.

These rigorous storage instructions make it a tiny bit tricky to travel with Dupixent. But don't worry, thousands of people travel with refrigerated medications, including people with diabetes, arthritis, Crohn's disease, glaucoma, and numerous other chronic conditions. They're doing just fine! All you need is a good organization and a reliable medical travel cooler.

Related article: Safety Tips for Traveling with Mild or Severe Asthma.

Dupixent travel kit

A portable cooler is essential to travel with Dupixent or any other medicine that requires refrigeration or room temperature cooling.

While some quickly pack their drugs into insulated lunch bags filled with a few ice cubes, these rudimentary DIY coolers aren't reliable enough for medications.

The safest and most convenient way to refrigerate Dupixent while traveling is to use a medical-grade travel cooler like the ones we've designed at 4AllFamily.

Dupixent travel kit, 4AllFamily USA

4AllFamily portable travel coolers for medicines

These are the safest and most performant travel coolers for medicines you can find on the market today. Depending on your needs, you can choose a model that works with gel packs, USB power, or even both!

Different options are available, from the lightest cooling bottle to the ultimate portable mini-fridge that offers temperature display and auto shut-off anti-freeze safety.

Our ultimate cooler can keep your Dupixent at constant fridge temperature 36-46°F / 2-8°C when plugged into any USB power source (car cigarette lighter, travel size power bank, portable USB solar panel, household power, etc.). So it's ideal for road trips, beach hotels, business travels, or even outdoor adventures with solar electricity!

When used without electricity (freeze-packs cooling method), the same cooler maintains fridge temperature for up to 52 hours when the outside temperature is 86°F / 30°C.

Our nomad cooling bottles would be more convenient if you prefer to pack as light as possible for your next trip. The smaller model is ideal for carrying 1 pen of Dupixent and can fit into your purse or backpack, while the bigger model allows you to refrigerate up to 3 Dupixent pens.

All our coolers are TSA-approved for airplane travel so that you can board the plane with your high-value refrigerated Dupixent syringes in your carry-on bag.

International travels with Dupixent

Flying or traveling internationally with medications implies preparation and sometimes some documentation. Fortunately, Dupixent is a widely used medicine, and most destination countries are familiar with it, so you shouldn't face any particular issue when crossing international borders or at the airport. However, here are a few tips and reminders to make your journey smoother.

Related article: Does asthma affect travel insurance?

Flying with injectable medicines like Dupixent

Since Dupixent is a liquid injectable medication, it's natural to wonder whether you can fly with it. The good news: TSA regulations allow you to bring medically necessary liquids, including injectables, in your carry-on.

Here's what to keep in mind when flying with Dupixent:

  • No liquid restrictions: TSA's liquid rules do not apply to medications, so you can bring as much Dupixent as you need.

  • Use your carry-on: Always pack Dupixent in your carry-on, not in checked luggage. Temperature and pressure in the cargo hold can damage the medication.

  • No need for plastic bags: Medications don't have to be placed in a quart-size plastic bag like other liquids, but they must be clearly packed for inspection.

  • Original packaging is best: Keep your pens or syringes in their original containers with readable labels to avoid delays during security screening.

  • Refrigeration is allowed: If your Dupixent needs to stay cool, you can bring a TSA-approved medical travel cooler on the plane. Models from brands like 4AllFamily are designed specifically for this purpose.

Related article: How to travel with refrigerated medications?

What documents do you need to travel with Dupixent?

If you're flying nationally to a USA destination, you don't necessarily need to show a prescription. However, your Dupixent pens or syringes should be labeled or kept in their original containers to be easily identifiable by the airport security staff.

If you're flying internationally, it's good practice to have a copy of your medical prescription and a doctor's note in some cases. Depending on your destination, you may be required to show the following documentation when traveling with Dupixent:

  • A letter from your doctor
  • Your medical prescriptions
  • A document from your pharmacy
  • A medical health card

You may need to translate these documents into your destination country's official language, but English is generally ok. If you have doubts, check with the authority of your destination country before departure. You can find more detailed information here:

Related article: How to travel with medications internationally?

travel coolers medical, 4AllFamily USA
📌 Key Takeaways: 
  • 🧊 Keep Dupixent refrigerated between 36°F-46°F (2°C-8°C) using a medical-grade travel cooler-never expose it to temps above 77°F (25°C).

  • 🛄 Always pack Dupixent in your carry-on-cargo hold conditions can ruin the medication.

  • 📝 Bring documentation like a prescription or doctor's note, especially for international travel.

  • TSA allows injectable medications, and coolers like 4AllFamily's are approved for air travel.

  • 🌍 Plan ahead to ensure Dupixent stays safe and effective during flights or trips abroad.

💬 We'd Love to Hear From You!

Have questions about flying with Dupixent? Tips for keeping your medication cool on the go? Or maybe a travel story to share?Drop a comment below-we'd love to hear your experience! Whether you're a seasoned traveler or preparing for your first trip with Dupixent, your insights could help others in the community. Let's support each other!

📆 Article Update History:

Updated: April 04, 2025

Originally Published: October 03, 2022

October 03, 2022

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The information presented in this article and its comment section is for informational purposes only and is not intended as a replacement for professional medical advice. Always consult with a qualified healthcare provider for any medical concerns or questions you may have.